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Risk Factors Following Transplant


                                                                                  Heart Transplantation: Version 7.0

Risk Factors Following Transplant


Risk Factors Associated with Decreased One-Year Survival Following Transplantation [1]

Variable

Odds Ratio

P-value

95% Confidence Interval

  Repeat Transplantation [2]

3.51

>0.0001

2.82-4.37

  Ventilator

2.39

>0.0001

1.91-2.99

  Center Volume < 9 TX/yr

1.29

0.0002

1.13-1.47

  ICU and Life Support

1.21

0.001

1.08-1.36

  Non-white recipient

1.18

0.01

1.04-1.34

  Cold Ischemic Time

1.13

>0.0001

1.08-1.19

  ABO not Type A

1.1

0.04

1.01-1.21

  Donor Female

1.22

>0.0001

1.10-1.35

  Non-white Donor

1.15

0.02

1.02-1.29

  Donor age (linear)

 

>0.0001

 

  Donor age (quadratic)

 

0.002

 

1 Baumgartner, WA. “Heart Transplantation.” Adult Cardiac Surgery FAQs CTSNet 2003. 16 June 2003

2 Relative risk factor. Patients retransplanted in the first year following initial transplantation because of acute rejection do poorly. Patients who are retransplanted many years after the initial transplantation because of transplant vasculopathy may do as well as first transplants.